Computer Simulations of Genetics Laws

Mankiran Singh², Gurmukh Singh¹, Khalid Siddiqui¹ and Satpal Singh²

 ¹Department of Computer and Information Sciences, SUNY at Fredonia, Fredonia, NY 14063

²Department of Pharmacology and Toxicology, SUNY at Buffalo, Buffalo, NY 14214

¹singh@fredonia.edu, siddiqui@fredonia.edu

²mankiran@buffalo.edu, singhs@buffalo.edu

Abstract - The most recent version of MS Visual Studio .NET 2010 software system has been employed to computer simulate Mendel’s laws of genetics in biology, biochemistry, biophysics, microbiology education in a virtual classroom setting. We developed the necessary computer algorithm using a built-in pseudo-random number generating function in MS Visual Studio .NET 2010, to computer model two Mendel’s Laws of heredity for plant and animal species. Over 36,000 computer simulations have been performed to investigate behaviour of recessive genes to verify Laws of heredity in genetics. Our simulations corroborate the experimental results of Mendel’s research on inheritance in Pisum hybrids. We compared our results of simulated data with those collected from experiments done on Drosophila melanogaster, which is extensively used as a model organism to study genetics and development, an exceedingly good agreement between these two data sets has been obtained for the F2 generation.

Keywords: MS Visual Studio .NET 2010, Software System, Mendel’s Laws, Drosophila melanogaster, Dominant and Recessive genes, Pisum Hybrids, Visual Basic Language, Simulations, Random Numbers, GUI.